Translational research into action

Right people to fill the gap

Strategic advances for funding opportunities need a team approach to promote and support the aim.

The search for successful partnerships requires real-world attitudes to build researcher capability in finding translational investigators focusing on filling the information gap of health service research.

Co-ordinating actions to enhance your profile of research capability and research capacity requires a Translational Research Co-ordinator. With supervision their strategies can make grant budgets profitable,

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What are they looking for?

Policy relevance with new policy or practice initiatives

Knowledge exchange with stakeholders prior to research commencement

Trusting support from an industry representative

University management in approval of funding

Best researchers for grant applications

Looking for a supportive partnership with grant opportunities, competitive research grants offer supportive resources at a national scale of impact.

Identify priority values of grant funders as:

• Regional applicants

• Financially committed to reporting progress and expenditure

• Researcher interest for diversity in project capacity

• Organised candidates with a structured team

• Organisational alignment with governmental strategies

• Supported by organisations considering practice change outcomes.

(New South Wales Government, 2018)

Active partnership with grant funding incorporates responsibility of encouraging and supporting public participation in relevant decisions impacting the community.

Positive experiences of health care fulfil compliance with the National Safety and Quality Health Service Standards.

Australian Safety and Quality Framework for Health Care

Keywords

Bond

planning of partnerships, education and training, support, information and communication, involvement of family and carers

Give

best practice, operational planning, active encouragement, respect, right to access, meets their individual needs, active role, health or community services, reasonable access to records of personal information, safe, explanation, priority setting, evaluation strategy, implementation of the standards

Connect

patient and consumer centred, care, consent, consumer experience, decisions, comfort, feedback, access to procedures, timely reporting, provide health services

Unite

responsive to patients, continuity and transition, develop action plans. recognition for their contribution, confidentiality, evaluation, ongoing management

Exchange

safety and quality and service improvement. health and wellbeing, continuous improvement activities, quality improvement, compliance, guidelines

(Government of South Australia, South Australia Health, 2013)

Healthcare services create opportunities for people to have a safe environment to gain quality healthcare.

In research, the provision of services affect the quality framework. Improvements in consumer centred data for care and safety are being driven by research to improve care.

Partnerships between consumers, health practitioners, clinicians and researchers form change in the community redesigning solutions and improving innovative health services.

Quality health builds capability and improves renewable capacity in the community.

How can we be part of the improvement?

Healthcare system

Improving the capabilities of research through the healthcare system increases translating research into action. Data and access to data, sharing for benefits to the community, generates research capability.

Healthcare management of organisational knowledge supports effective strategy and well-organised focus.

The solution is building capacity in the healthcare system in Australia to translate the best possible research into action (Evans, Brown & Baker, 2017).

Provider

Expertise and dedication require resources to develop unit-based gap analysis tools specific to implementing. Action plans, gap analysis and tests of change set goals to improve latest developments of evidence-based interventions. Communicating with consumers complete and timely information increases translation (Australian Commission on Safety & Quality in Health Care, n.d).

Training for health care providers to develop programs, protocols and services improve care delivery,

Team collaboration can effect up to 70% of the adverse events in patient outcomes (Fewster-Thuente & Velsor-Friedrich. 2008).

Access, it is important to understand, includes lifestyle choices, which in healthcare, contributes to disparities in quality and safety (Riley, 2012).

Program

With aim, programs innovating advanced research use models for new treatments into the community.

Building research capability focuses on implementation of evidence-based interventions. Understanding

the processes of new applications impact strategies with the use of analysed existing and new data.

Leadership develops systematic review, mentoring impacting the quality of mentee's skills and the abilities in an organisation which benefits performance and quality.

Consumers

Involving consumers to implement promotional events strengthens disseminating of research information.

In research activities, effectively, visualisation of data, new opportunities and highest ethical standards

implements research funding.

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Confidence in the pathway

Finding solutions

Strategic and responsive grant making

Comparative effectiveness

Consistency

Finding solutions

With 80 years of experience the National Health and Medical Research Council (NHMRC) have promoted health services research (HSR) excellence.

Focus with Advanced Health Research and Translation Centre (AHRTC) partnerships strategise with local health districts, hospital networks, universities and medical research institutes to:

• promote communication, respect and collegiality among leading researchers

• exchange different viewpoints between researchers and policymakers, managers, clinicians and other interested parties

• translate policies and practices locally, nationally and internationally.

Justifiable research priorities for practitioner–scientist partnership networks achieve regulation and management of research, accessible with well-designed methodology and findings for risk reductions improving systems to deliver evidence-based interventions.

Research that is active and practical in application funded for knowledge translation, makes reliable, influential solutions.

Policy changes supporting research and development guide the continuum of healthcare.

Strategic and responsive grant making

Accomplishing goals with realistic planning develops real confidence in research funding and develops funder reputation.

Communication increases support for grantees, collaborative partnerships, relationships with the community and investor accomplishments and knowledge monitoring.

Main differences enabling researcher direction are:

Strategic grants

Specific issues making impact

Planning with direction

Time efficiency with organisation involvement

Responsive grants

Responsive new ideas

Rapid response to needs

Community research

Ease with planning

Appropriate, meaningful, and effective outcomes

Access nonprofits with eligibility opportunities for funding

Strategic foundations bring leadership, being open and aiming to more strategic grants unite private, nonprofits and government investors to be of the problem-driven funder solution in social issues to promote innovation and prosperity (Australian Government, Department of Industry, Innovation and Science, 2017).

Organisations build capacity and capability with research addressing emerging needs. Supporting the community, responsive funding grants with regional goals enable non-profit organisations to rapidly respond to needs with broader impact.

The highest quality of data requires meaningful and useful information being transformed into leading research of excellence linking a continuum of care while protecting the community.

Elements of design form interesting components of the process.

Figure 1. NSW Ministry of Health and the Sax Institute - Translational Research Framework (2018).

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Design

Hybrid research study designs give better understanding of the results, relating data with impact.

High-level focus of trial stages, avoiding two or more methods of research on same participants, consistency of participants within each stage and flexibility in order of stages advantage the study (McNeill, 2018).

Mixed-methods study designs help with understanding implementation challenges,

Their high reliability contributes to important new methodologies in training the researcher, with improvements in skills and professional experiences.

Pragmatic trials are valuable in assessing effectiveness of interventions and their outcomes.

Community-based participatory research offers new moral alignment with governmental goals, principles of health, policy guidelines and evidence (Taljaard et al., 2018).

Challenges

Discovering research evidence is a trial of evolving information into implementation in alignment with effective standards successful in reaching goals of good health.

With evidence based practice and clinical judgement best recommendations provide support and advice to providers.

Limitations on applicability: organisational, financial, personal intuition, expert experience, communication and access challenge researchers using their findings for practice (Mauricio Barría P, 2018).

A culture promoting research evidence among decision makers aim on the social determinants of health,

Translation of applied, comparative, clinical, investigator-Initiated, population health, targeted research, addresses real-world issues for useful preventative therapeutic interventions and treatments towards effectiveness outcomes,

Sufficient research making translation more evidence based supports enduring, quality, reliable data for

guidelines, policy, and service development.

Reducing barriers of uncertainty and risk

Unnecessary risk can be eliminated, evidence-practice and policy gaps can be defined and distributed for optimal healthcare, avoiding significant costs with a lasting impression.

Barriers within the healthcare system include:

- unsafe interventions and treatments with unfavourable health effects needing strategic policy changes

- lack of provider training to successfully convey purposeful information for shared understanding

- management making decisions turning into situations of laborious tasks.

Research acceleration

Community engagement needs direct encouragement and integration.

Stakeholders trust direct project researchers by sharing the recommendations of potential risks.

increasing the value of stakeholder relationships.

Accurate research and diligent reporting build trust among partnerships, while respectful expertise

and outreach efforts with community-driven decision-making contribution to patient centred care.

Consumer

Community group

Provider

Clinical trial group

Governmental agency

The National Health and Medical Research Council (NHMRC)/Consumers Health Forum of Australia (CHF) joint Statement facilitates active consumer involvement with research funding in all levels of health and medical research (Australian Government, National Health and Medical Research Council, 2016).

Valuable insight promotes quality and relevance of research, activity and direction make opportunities for achievements in health improvement.

Collaboration of stakeholders with a system-level understanding of national changes in structure and function helps aim to scale capacity and eliminate performance risks.

To design future strategies, partnerships use solutions to build resources for implementation, sustainability and profitability.

Discussions are needed to share views and expertise, plan and offer important local knowledge, and connect.

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Resource Guide for Collaboration

NHMRC

Annual NHMRC Research Translation Symposium

Advanced Health Research and Translation Centres

Members of the Health Translation Advisory Committee

Guideline Development Group

Peer Review Grant Implementations

Health System Sustainability NHMRC Partnership Centre

Research Organisations

Australian Primary Health Care Research Institute

Translation Research Institute Australia

Translational Research Symposium

Statewide Translation Research Showcases

Statewide Translational Research Networks

Statewide Health Alliances

Pacific Health Governance Research Network

The Health-Science Alliance

Cochrane Australia - Research

Australian Phenomics Network

Non Profit Organisations

Research Organisations

Consumer & Community Health Research Networks

Medical Research Institutes

National/Sector Specific Research Groups

National/Sector Specific Societies

National Study Groups

National Trials Groups

Universities

University Translational Research Forums

University Translational Research Symposiums

Research Platforms

Australian Clinical Trials Registry

Australian Clinical Trials Alliance

Statistics in Trials Interest Group

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Integration of ethical tools

With new approaches to analyse knowledge, steps and phases, translational research ethics allow for advancements in development of new research.

Bioethical clinical endpoint analysis tools specifically directed to improving efficiency in transdisciplinary research can analyse phases with a database and compare components of past implementations and new initiatives with principles of ethics (Hostiuc et al., 2016).

Development of financial interests

Opportunities for researchers can take years of discovery and development, funders want to see reputations of their researchers based on excellence outcomes.

Pharmaceutical, medical device, and biotechnology companies can improve goals of healthcare. Alignment with governmental and researcher priorities strengthen impact of recommendations.

Industries seeking to partner with the enterprise spirit of academic researchers need to recognise researcher ownership and publication control.

University-related startups companies developing translational research are seen by the Australian Government as an indication of their contribution to the national economy.

Universities need more security preventions to collaborate with industry partners. Clinical research is best when

aligned more with industry business solutions, financial benefits and competitor advantage than University interests.

Public concerns for research

Proper recognition and management of financial commitments are essential for approval of funding and to reduce limitations in research.

Universities aiming to commercialise research can disturb the mission and focus of open publications and education.

With access to financial support and benefits from endorsers, standards are easier to maintain, training for professional development earn credentials, proper functioning adherence is to research policies for compliance and trustworthy outcomes for consumers can be measured.

New regulations are needed in financial management of research grants and personal financial endorsement to make safe research to protect human participants and regulate costs.

Studies of longer duration increase costs with of participants and need technological resources to sustain productivity (Raudenbush & Xiao-Feng, 2001).

Disclosure of financial research should not affect willingness of participants.

Avoiding institutional conflicts of interest, tracking actions of industry will apply compliance and ethics monitoring of health outcome.

Industry related struggles

Being part of the global research translating a transforming industry with the least outcomes of financial risk minimises a specific problem, cost.

Broadening analysis of the following knowledge with variations and historical evidence is most successful with:

- accurate, honest, impacting information from studies

- reliable data qualitative and quantitative aspects of the industry

- characteristics of ranking difference levels of solutions and their stages

- stakeholder partnerships and attributes for best outcomes.

Correlations using technology could summarise strong positive correlations and help allocate a easier path for researchers to have access to connect with experts with knowledge in effective evaluation of costs. Corrective evaluation benefits action planning to implement alternative therapies and interventions or improve them.

Changing struggles in healthcare of beyond management need:

- Treatment guidelines informing best practices to give direction for best clinical research.

- Promotion of interest with more visual representations of the research.

- Deliverable responsive engagement of successes to stakeholders.

- Relevance of research in the context of regional characteristic, traditions and beliefs.

- Use of all data in all stages of translation.

- Options for flexibility of methods and approaches.

- Evidence on public health inequalities.

- Communicating processes by influencing how people perceive current and emerging risks.

Aiming for valuable scientific knowledge is important for interactive research spaces incorporating technological collaboration to stream-time with time-tracking and activity tracking showing evidence to benefit with trustworthy decision making.

Management, innovation and value from all levels of stakeholders initiates consultation for awareness and recognition of challenges, in specific areas to design policies supporting an adaptive honest culture towards health, social justice and political mobilization.

References

Aldwin, C., & Greenberger, E. (1987). Cultural differences in the predictors of depression. American Journal of Community Psychology, 15, 789-813. doi:10.1007/BF00919803

Auld, R., Loppacher, T., Rose, S., Milat, A. J., & Penna, A. (2018). Translational Research Grants Scheme (TRGS): A new approach to strengthening health system research capacity. Public Health Research and Practice, 28(3). e2831818.

Evans, J. M., Brown, A., & Baker, G. R. (2017). Organizational knowledge and capabilities in healthcare: Deconstructing and integrating diverse perspectives. Sage Open Medicine, 5, 1-10. doi: 10.1177/2050312117712655

Australian Commission on Safety and Quality in Health Care. (n.d.). Australian safety and quality framework for health care: Putting the framework into action: Getting started. Sydney, NSW: Australia. Australian Commission on Safety and Quality in Healthcare. Retrieved from https://www.safetyandquality.gov.au/wp-content/uploads/2011/01/ASQFHC-Guide-Healthcare-team.pdf

Australian Government, Department of Industry, Innovation and Science. (2017). Australia 2030: Prosperity through innovation. Canberra, ACT: Australia. Retrieved from https://www.industry.gov.au/data-and-publications/australia-2030-prosperity-through-innovation

Australian Government, National Health and Medical Research Council. (2016). Statement on consumer and community involvement in health and medical research. Canberra, ACT: Australia. National Health and Medical Research Council. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161426/

Barría R. M. (2018). The gap remains: The challenge of translating research into policies for the health care of people and communities. Investigación y Educación en Enfermería, 35(2), 129-130. doi: 10.17533/udea.iee.v35n2a01

Building capacity and capability for improvement: embedding quality improvement skills in NHS providers. (2017). Retrieved February 11, 2019, from the National Health Services Improvement, London, National Health Services Improvement Web site: https://improvement.nhs.uk/documents/1660/01-NHS107-Dosing_Document-010917_K_1.pdf

Fewster-Thuente, L., & Velsor-Friedrich. B. (2008). Interdisciplinary collaboration for healthcare professionals. Nursing Administration Quarterly, 32(1), 40-8. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/18160862

Government of South Australia, SA Health. (2013). Policy, directive: Compliance is mandatory. Adelaide, SA: Australia. Department for Health and Ageing, Government of South Australia. Retrieved from https://www.sahealth.sa.gov.au/wps/wcm/connect/59bbc2804e45470da9e9af8ba24f3db9/Directive_Framework+for+Active_Partnership_V1.4_29.11.18.pdf?MOD=AJPERES&CACHEID=ROOTWORKSPACE-59bbc2804e45470da9e9af8ba24f3db9-mtNjAdy

Hostiuc, S., Moldoveanu, A., Dascălu, M., Unnthorsson, R., Jóhannesson, O. I., & Marcus, I. (2016). Translational research—the need of a new bioethics approach. Journal of Translational Medicine, 14:(16), doi: 10.1186/s12967-016-0773-4

McNeill, C. (March, 2018). Hybrid research: Combining qualitative and quantitative methods and more, Retrieved from https://www.gutcheckit.com/blog/hybrid-research/

NSW Government. NSW Ministry of Health. (2018). Translational Research Grants Scheme Round 4. North Sydney, NSW: Australia. NSW Ministry of Health. Retrieved from https://www.medicalresearch.nsw.gov.au/wp-content/uploads/2018/08/Translational-Research-Grants-Scheme-Round-4_Final.pdf

Raudenbush, S. W., & Xiao-Feng, L. (2001). Effects of study duration, frequency and observation, and sample size on power in studies with group differences with polynomial change. Psychological Methods, 6(4), 387-401. doi: 10.1037//1082989X.6.4.387

Riley, W. J. (2012). Health disparities: Gaps in access, quality and affordability of medical care. Transactions of the American Clinical and Climatological Association, 123, 167–174. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540621/

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